Detoxified CT and CTB have also been extensively studied in individuals with couple of side-effects [27], and recombinant CTB is a element of the at present licensed oral cholera vaccine Dukoral
The nontoxic A2 domain of CTA passes by the central pore of CTB, tethering the A and B subunits jointly by non-covalent interactions . CT secreted by V. cholerae binds…