However, the aggregates co-localized with the autophagosomal marker LC3, pointing to the possibility that the W3566 Syn I mutant protein may possibly be directed to autophagy-mediated degradation
On the opposite, the W3566 isoform displayed cytosolic aggregates that neither linked with actin filaments nor caused gross cytoskeletal alterations (Determine 3A). To characterize the mother nature of these aggregates,…