Product Name :
SU11652
Sequence:
Purity:
≥98% (HPLC)
Molecular Weight:
414.9
Solubility :
Soluble in DMSO (>25 mg/ml).
Appearance:
Orange solid.
Use/Stability :
As indicated on product label or CoA when stored as recommended.3011029-58-3 References Stable for at least 6 months after receipt whenstored at -20°C.
Description:
VEGFR inhibitor Potent, ATP-competitive and cell permeable inhibitor of tyrosine kinases (VEGF-R2 IC50=27nM, PDGF-Rβ IC50=3nM). Also inhibits wild-type and all mutant forms of Kit in mast cells (IC50‘s=10 to 100nM) resulting in cell cycle arrest and apoptosis. Su11652 was also shown to induce autophagy in MCF-7 cells.
CAS :
326914-10-7
Solubility:
Soluble in DMSO (>25 mg/ml).
Formula:
C22H27ClN4O2
Additional Information :
| Alternative Name 5-[5-Chloro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide | Appearance Orange solid.154447-36-6 supplier | CAS 326914-10-7 | Couple Target VEGFR | Couple Type Inhibitor | Formula C22H27ClN4O2 | MW 414.PMID:30020653 9 | Purity ≥98% (HPLC) | Solubility Soluble in DMSO (>25 mg/ml). | Unit of Measure (UM) mg