Product Name :
Aristolactam I
Description:
Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage. Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway.
CAS:
13395-02-3
Molecular Weight:
293.27
Formula:
C17H11NO4
Chemical Name:
14-methoxy-3, 5-dioxa-10-azapentacyclo[9.7.1.0, .0, .0, ]nonadeca-1(18), 2(6), 7, 11(19), 12, 14, 16-heptaen-9-one
Smiles :
COC1=CC=CC2C3=C4C(=CC=21)NC(=O)C4=CC1OCOC=13
InChiKey:
MXOKGWUJNGEKBH-UHFFFAOYSA-N
InChi :
InChI=1S/C17H11NO4/c1-20-12-4-2-3-8-9(12)5-11-14-10(17(19)18-11)6-13-16(15(8)14)22-7-21-13/h2-6H,7H2,1H3,(H,18,19)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage.Apraglutide GPCR/G Protein Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway.Tiamulin supplier |Product information|CAS Number: 13395-02-3|Molecular Weight: 293.PMID:32809584 27|Formula: C17H11NO4|Synonym:|Aristololactam|Aristolactam|Chemical Name: 14-methoxy-3, 5-dioxa-10-azapentacyclo[9.7.1.0, .0, .0, ]nonadeca-1(18), 2(6), 7, 11(19), 12, 14, 16-heptaen-9-one|Smiles: COC1=CC=CC2C3=C4C(=CC=21)NC(=O)C4=CC1OCOC=13|InChiKey: MXOKGWUJNGEKBH-UHFFFAOYSA-N|InChi: InChI=1S/C17H11NO4/c1-20-12-4-2-3-8-9(12)5-11-14-10(17(19)18-11)6-13-16(15(8)14)22-7-21-13/h2-6H,7H2,1H3,(H,18,19)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Li J, et al. Toxicities of aristolochic acid I and aristololactam I in cultured renal epithelial cells. Toxicol In Vitro. 2010 Jun;24(4):1092-7.Products are for research use only. Not for human use.|