Product Name :
Mca-Ala-Pro-Lys(Dnp)-OH
Description:
Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung.
CAS:
305336-82-7
Molecular Weight:
696.66
Formula:
C32H36N6O12
Chemical Name:
(2S)-6-[(2,4-dinitrophenyl)amino]-2-{[(2S)-1-[(2S)-2-[2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetamido]propanoyl]pyrrolidin-2-yl]formamido}hexanoic acid
Smiles :
C[C@H](NC(=O)CC1=CC(=O)OC2=CC(=CC=C12)OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCNC1=CC=C(C=C1[N+]([O-])=O)[N+]([O-])=O)C(O)=O
InChiKey:
INOZJECNSBDPGT-WDNCENIBSA-N
InChi :
InChI=1S/C32H36N6O12/c1-18(34-28(39)14-19-15-29(40)50-27-17-21(49-2)9-10-22(19)27)31(42)36-13-5-7-25(36)30(41)35-24(32(43)44)6-3-4-12-33-23-11-8-20(37(45)46)16-26(23)38(47)48/h8-11,15-18,24-25,33H,3-7,12-14H2,1-2H3,(H,34,39)(H,35,41)(H,43,44)/t18-,24-,25-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Bathophenanthroline} site|{Bathophenanthroline} {Fluorescent Dye}|{Bathophenanthroline} Purity & Documentation|{Bathophenanthroline} Purity|{Bathophenanthroline} manufacturer|{Bathophenanthroline} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.{{Bromobenzene-d5} medchemexpress|{Bromobenzene-d5} Cytochrome P450|{Bromobenzene-d5} Purity & Documentation|{Bromobenzene-d5} Formula|{Bromobenzene-d5} supplier|{Bromobenzene-d5} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32310547
Additional information:
Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung.|Product information|CAS Number: 305336-82-7|Molecular Weight: 696.66|Formula: C32H36N6O12|Chemical Name: (2S)-6-[(2,4-dinitrophenyl)amino]-2-{[(2S)-1-[(2S)-2-[2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetamido]propanoyl]pyrrolidin-2-yl]formamido}hexanoic acid|Smiles: C[C@H](NC(=O)CC1=CC(=O)OC2=CC(=CC=C12)OC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCNC1=CC=C(C=C1[N+]([O-])=O)[N+]([O-])=O)C(O)=O|InChiKey: INOZJECNSBDPGT-WDNCENIBSA-N|InChi: InChI=1S/C32H36N6O12/c1-18(34-28(39)14-19-15-29(40)50-27-17-21(49-2)9-10-22(19)27)31(42)36-13-5-7-25(36)30(41)35-24(32(43)44)6-3-4-12-33-23-11-8-20(37(45)46)16-26(23)38(47)48/h8-11,15-18,24-25,33H,3-7,12-14H2,1-2H3,(H,34,39)(H,35,41)(H,43,44)/t18-,24-,25-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 50 mg/mL (71.77 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|The activity of ACE2 enzyme detected by: the fluorescent peptide substrate Mca-AlaPro-Lys (Dnp)-OH is hydrolyzed by ACE2 and its product is detected by the active fluorescence resonance energy transfer method.|Products are for research use only. Not for human use.|