Product Name :
Tigloylgomisin H
Description:
Tigloylgomisin H is a lignan isolated from the fruits of S. chinensis, can induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. Tigloylgomisin H functions as a monofunctional inducer that specifically upregulates phase II detoxification enzyme NQO1 through the NF-E2-related factor 2 (Nrf2)-ARE pathway, thus represents a potential liver cancer prevention agent.
CAS:
66069-55-4
Molecular Weight:
500.58
Formula:
C28H36O8
Chemical Name:
(9S,10S)-10-hydroxy-4,5,14,15,16-pentamethoxy-9,10-dimethyltricyclo[10.4.0.0²,⁷]hexadeca-1(16),2,4,6,12,14-hexaen-3-yl (2E)-2-methylbut-2-enoate
Smiles :
C/C(=C\C)/C(=O)OC1=C2C3=C(OC)C(OC)=C(C=C3C[C@](C)(O)[C@@H](C)CC2=CC(OC)=C1OC)OC
InChiKey:
ZSAUXCVJDYCLRS-QEEHVONISA-N
InChi :
InChI=1S/C28H36O8/c1-10-15(2)27(29)36-26-21-17(12-19(31-5)24(26)34-8)11-16(3)28(4,30)14-18-13-20(32-6)23(33-7)25(35-9)22(18)21/h10,12-13,16,30H,11,14H2,1-9H3/b15-10+/t16-,28-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Tigloylgomisin H is a lignan isolated from the fruits of S. chinensis, can induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. Tigloylgomisin H functions as a monofunctional inducer that specifically upregulates phase II detoxification enzyme NQO1 through the NF-E2-related factor 2 (Nrf2)-ARE pathway, thus represents a potential liver cancer prevention agent.|Product information|CAS Number: 66069-55-4|Molecular Weight: 500.58|Formula: C28H36O8|Chemical Name: (9S,10S)-10-hydroxy-4,5,14,15,16-pentamethoxy-9,10-dimethyltricyclo[10.{{BCMA/TNFRSF17 Protein, Human} medchemexpress|{BCMA/TNFRSF17 Protein, Human} Protocol|{BCMA/TNFRSF17 Protein, Human} Description|{BCMA/TNFRSF17 Protein, Human} manufacturer|{BCMA/TNFRSF17 Protein, Human} Epigenetic Reader Domain} 4.{{Glibornuride} web|{Glibornuride} Potassium Channel|{Glibornuride} Immunology/Inflammation|{Glibornuride} Protocol|{Glibornuride} Description|{Glibornuride} manufacturer} 0.PMID:23910527 0²,⁷]hexadeca-1(16),2,4,6,12,14-hexaen-3-yl (2E)-2-methylbut-2-enoate|Smiles: C/C(=C\C)/C(=O)OC1=C2C3=C(OC)C(OC)=C(C=C3C[C@](C)(O)[C@@H](C)CC2=CC(OC)=C1OC)OC|InChiKey: ZSAUXCVJDYCLRS-QEEHVONISA-N|InChi: InChI=1S/C28H36O8/c1-10-15(2)27(29)36-26-21-17(12-19(31-5)24(26)34-8)11-16(3)28(4,30)14-18-13-20(32-6)23(33-7)25(35-9)22(18)21/h10,12-13,16,30H,11,14H2,1-9H3/b15-10+/t16-,28-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|