Product Name :
GSK2292767
Description:
GSK2292767 is a potent and selective PI3Kδ inhibitor.
CAS:
1254036-66-2
Molecular Weight:
512.58
Formula:
C24H28N6O5S
Chemical Name:
N-[5-(4-{5-[(2,6-dimethylmorpholin-4-yl)methyl]-1,3-oxazol-2-yl}-1H-indazol-6-yl)-2-methoxypyridin-3-yl]methanesulfonamide
Smiles :
COC1N=CC(=CC=1NS(C)(=O)=O)C1=CC2NN=CC=2C(=C1)C1=NC=C(CN2CC(C)OC(C)C2)O1
InChiKey:
NLUPPCTVKHDVIQ-UHFFFAOYSA-N
InChi :
InChI=1S/C24H28N6O5S/c1-14-11-30(12-15(2)34-14)13-18-9-26-23(35-18)19-5-16(6-21-20(19)10-27-28-21)17-7-22(29-36(4,31)32)24(33-3)25-8-17/h5-10,14-15,29H,11-13H2,1-4H3,(H,27,28)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
GSK2292767 is a potent and selective PI3Kδ inhibitor.|Product information|CAS Number: 1254036-66-2|Molecular Weight: 512.58|Formula: C24H28N6O5S|Chemical Name: N-[5-(4-{5-[(2,6-dimethylmorpholin-4-yl)methyl]-1,3-oxazol-2-yl}-1H-indazol-6-yl)-2-methoxypyridin-3-yl]methanesulfonamide|Smiles: COC1N=CC(=CC=1NS(C)(=O)=O)C1=CC2NN=CC=2C(=C1)C1=NC=C(CN2CC(C)OC(C)C2)O1|InChiKey: NLUPPCTVKHDVIQ-UHFFFAOYSA-N|InChi: InChI=1S/C24H28N6O5S/c1-14-11-30(12-15(2)34-14)13-18-9-26-23(35-18)19-5-16(6-21-20(19)10-27-28-21)17-7-22(29-36(4,31)32)24(33-3)25-8-17/h5-10,14-15,29H,11-13H2,1-4H3,(H,27,28)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Solubility (25°C).{{Taldefgrobep alfa} medchemexpress|{Taldefgrobep alfa} Protocol|{Taldefgrobep alfa} Purity|{Taldefgrobep alfa} manufacturer|{Taldefgrobep alfa} Autophagy} 100 mg/mL(195.{{Bongkrekic acid} site|{Bongkrekic acid} Membrane Transporter/Ion Channel|{Bongkrekic acid} Purity & Documentation|{Bongkrekic acid} In stock|{Bongkrekic acid} supplier|{Bongkrekic acid} Cancer} 09 mM).PMID:24187611 Insoluble.|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|GSK2292767 is highly selective for PI3Kδ over the closely related isoforms and is active in a disease relevant brown Norway rat acute OVA model of Th2-driven lung inflammation.|Products are for research use only. Not for human use.|