Product Name :
Asenapine maleate
Description:
Asenapine, also known as Org 5222 and HSDB 8061, shows high affinity (pKi) for numerous receptors, including the serotonin 5-HT1A (8.6), 5-HT1B (8.4), 5-HT2A (10.2), 5-HT2B (9.8), 5-HT2C (10.5), 5-HT5A (8.8), 5-HT6 (9.5), and 5-HT7 (9.9) receptors, the adrenergic α1 (8.9), α2A (8.9), α2B (9.5), and α2C (8.9) receptors, the dopamine D1 (8.9), D2 (8.9), D3 (9.4), and D4 (9.0) receptors, and the histamine H1 (9.0) and H2 (8.2) receptors. Asenapine behaves as an antagonist at all receptors. It exhibits potent activity in animal models predictive of antipsychotic efficacy.
CAS:
85650-56-2
Molecular Weight:
401.84
Formula:
C21H20ClNO5
Chemical Name:
(2S,6S)-17-chloro-4-methyl-13-oxa-4-azatetracyclo[12.4.0.0²,⁶.0⁷,¹²]octadeca-1(14),7,9,11,15,17-hexaene; (2Z)-but-2-enedioic acid
Smiles :
CN1C[C@H]2[C@H](C1)C1=CC(Cl)=CC=C1OC1=CC=CC=C12.OC(=O)/C=C\C(O)=O
InChiKey:
GMDCDXMAFMEDAG-CHHFXETESA-N
InChi :
InChI=1S/C17H16ClNO.C4H4O4/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19;5-3(6)1-2-4(7)8/h2-8,14-15H,9-10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,15-;/m1./s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Asenapine, also known as Org 5222 and HSDB 8061, shows high affinity (pKi) for numerous receptors, including the serotonin 5-HT1A (8.{{Pemetrexed} MedChemExpress|{Pemetrexed} Antifolate|{Pemetrexed} Purity & Documentation|{Pemetrexed} References|{Pemetrexed} supplier|{Pemetrexed} Epigenetics} 6), 5-HT1B (8.4), 5-HT2A (10.2), 5-HT2B (9.8), 5-HT2C (10.5), 5-HT5A (8.8), 5-HT6 (9.5), and 5-HT7 (9.9) receptors, the adrenergic α1 (8.9), α2A (8.9), α2B (9.5), and α2C (8.9) receptors, the dopamine D1 (8.9), D2 (8.9), D3 (9.4), and D4 (9.0) receptors, and the histamine H1 (9.0) and H2 (8.2) receptors. Asenapine behaves as an antagonist at all receptors. It exhibits potent activity in animal models predictive of antipsychotic efficacy.|Product information|CAS Number: 85650-56-2|Molecular Weight: 401.84|Formula: C21H20ClNO5|Chemical Name: (2S,6S)-17-chloro-4-methyl-13-oxa-4-azatetracyclo[12.{{Terizidone} MedChemExpress|{Terizidone} Anti-infection|{Terizidone} Protocol|{Terizidone} Formula|{Terizidone} supplier|{Terizidone} Autophagy} 4.PMID:23710097 0.0²,⁶.0⁷,¹²]octadeca-1(14),7,9,11,15,17-hexaene; (2Z)-but-2-enedioic acid|Smiles: CN1C[C@H]2[C@H](C1)C1=CC(Cl)=CC=C1OC1=CC=CC=C12.OC(=O)/C=C\C(O)=O|InChiKey: GMDCDXMAFMEDAG-CHHFXETESA-N|InChi: InChI=1S/C17H16ClNO.C4H4O4/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19;5-3(6)1-2-4(7)8/h2-8,14-15H,9-10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,15-;/m1./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|