Product Name :
Propargyl-PEG7-acid
Description:
Propargyl-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
2093154-00-6
Molecular Weight:
392.44
Formula:
C18H32O9
Chemical Name:
4,7,10,13,16,19,22-heptaoxapentacos-24-ynoic acid
Smiles :
C#CCOCCOCCOCCOCCOCCOCCOCCC(O)=O
InChiKey:
VCXGERMSMMAGNQ-UHFFFAOYSA-N
InChi :
InChI=1S/C18H32O9/c1-2-4-21-6-8-23-10-12-25-14-16-27-17-15-26-13-11-24-9-7-22-5-3-18(19)20/h1H,3-17H2,(H,19,20)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Nobiletin} MedChemExpress|{Nobiletin} ROR|{Nobiletin} Protocol|{Nobiletin} In Vitro|{Nobiletin} supplier|{Nobiletin} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Aprepitant-d4} web|{Aprepitant-d4} {Isotope-Labeled Compounds}|{Aprepitant-d4} Protocol|{Aprepitant-d4} In Vitro|{Aprepitant-d4} supplier|{Aprepitant-d4} Cancer}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Propargyl-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).PMID:32472497 |Product information|CAS Number: 2093154-00-6|Molecular Weight: 392.44|Formula: C18H32O9|Chemical Name: 4,7,10,13,16,19,22-heptaoxapentacos-24-ynoic acid|Smiles: C#CCOCCOCCOCCOCCOCCOCCOCCC(O)=O|InChiKey: VCXGERMSMMAGNQ-UHFFFAOYSA-N|InChi: InChI=1S/C18H32O9/c1-2-4-21-6-8-23-10-12-25-14-16-27-17-15-26-13-11-24-9-7-22-5-3-18(19)20/h1H,3-17H2,(H,19,20)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.|Products are for research use only. Not for human use.|