Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of CP 472295 site diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This short article is distributed under the terms on the Creative Commons Attribution-NonCommercial three.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits noncommercial use, reproduction and distribution of your work without having additional permission provided the original operate is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).two water content, volume, or frequency of stools.11 A decrease in consistency (ie, soft or liquid) and an increase inside the frequency of bowel movements to 3 stools per day have frequently been used as a definition for epidemiological investigations. Depending on a community-based study point of view, diarrhea is defined as no less than three or extra loose stools within a 24-hour period.12 A diarrheal episode is regarded because the passage of 3 or far more loose or liquid stools in 24 hours before presentation for care, which can be thought of by far the most practicable in young children and adults.13 Nevertheless, prolonged and persistent diarrhea can final among 7 and 13 days and at least 14 days, respectively.14,15 The illness is hugely sensitive to climate, showing seasonal variations in a lot of web-sites.16 The climate sensitivity of diarrheal disease is consistent with observations with the direct effects of climate variables around the RWJ 64809 web causative agents. Temperature and relative humidity have a direct influence on the price of replication of bacterial and protozoan pathogens and on the survival of enteroviruses within the atmosphere.17 Well being care journal.pone.0169185 in search of is recognized to be a outcome of a complex behavioral approach that may be influenced by various factors, like socioeconomic and demographic and characteristics, perceived have to have, accessibility, and service availability.Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This article is distributed below the terms of the Creative Commons Attribution-NonCommercial three.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits noncommercial use, reproduction and distribution with the function without having additional permission provided the original perform is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).two water content, volume, or frequency of stools.11 A decrease in consistency (ie, soft or liquid) and an increase inside the frequency of bowel movements to three stools per day have often been utilised as a definition for epidemiological investigations. According to a community-based study viewpoint, diarrhea is defined as at the very least three or additional loose stools within a 24-hour period.12 A diarrheal episode is considered because the passage of three or additional loose or liquid stools in 24 hours prior to presentation for care, which can be deemed one of the most practicable in kids and adults.13 Nonetheless, prolonged and persistent diarrhea can final involving 7 and 13 days and at the least 14 days, respectively.14,15 The disease is extremely sensitive to climate, showing seasonal variations in many web sites.16 The climate sensitivity of diarrheal disease is constant with observations of the direct effects of climate variables around the causative agents. Temperature and relative humidity have a direct influence around the rate of replication of bacterial and protozoan pathogens and on the survival of enteroviruses in the environment.17 Wellness care journal.pone.0169185 seeking is recognized to become a result of a complex behavioral process that is certainly influenced by numerous elements, such as socioeconomic and demographic and traits, perceived require, accessibility, and service availability.