Product Name :
Thrombin inhibitor 1
Description:
Thrombin inhibitor 1 is a potent thrombin inhibitor (Ki=0.66 nM, 2xaPTT=0.43 μM).
CAS:
855998-46-8
Molecular Weight:
497.32
Formula:
C22H20Cl2F2N4O3
Chemical Name:
2-(3-chloro-6-[2,2-difluoro-2-(1-oxo-1λ⁵-pyridin-2-yl)ethyl]amino-1-oxo-1λ⁵-pyridin-2-yl)-N-[(1R)-1-(3-chlorophenyl)ethyl]acetamide
Smiles :
C[C@@H](NC(=O)CC1=C(Cl)C=CC(NCC(F)(F)C2=CC=CC=N2=O)=N1=O)C1=CC(Cl)=CC=C1
InChiKey:
ISTCYDGUBPNUDF-CQSZACIVSA-N
InChi :
InChI=1S/C22H20Cl2F2N4O3/c1-14(15-5-4-6-16(23)11-15)28-21(31)12-18-17(24)8-9-20(30(18)33)27-13-22(25,26)19-7-2-3-10-29(19)32/h2-11,14,27H,12-13H2,1H3,(H,28,31)/t14-/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Thrombin inhibitor 1 is a potent thrombin inhibitor (Ki=0.66 nM, 2xaPTT=0.43 μM).|Product information|CAS Number: 855998-46-8|Molecular Weight: 497.32|Formula: C22H20Cl2F2N4O3|Chemical Name: 2-(3-chloro-6-[2,2-difluoro-2-(1-oxo-1λ⁵-pyridin-2-yl)ethyl]amino-1-oxo-1λ⁵-pyridin-2-yl)-N-[(1R)-1-(3-chlorophenyl)ethyl]acetamide|Smiles: C[C@@H](NC(=O)CC1=C(Cl)C=CC(NCC(F)(F)C2=CC=CC=N2=O)=N1=O)C1=CC(Cl)=CC=C1|InChiKey: ISTCYDGUBPNUDF-CQSZACIVSA-N|InChi: InChI=1S/C22H20Cl2F2N4O3/c1-14(15-5-4-6-16(23)11-15)28-21(31)12-18-17(24)8-9-20(30(18)33)27-13-22(25,26)19-7-2-3-10-29(19)32/h2-11,14,27H,12-13H2,1H3,(H,28,31)/t14-/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Insulin (human) TGF-beta/Smad |Shelf Life: ≥12 months if stored properly.Sotigalimab Autophagy |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32552136 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Thrombin inhibitor 1 (Compound 4) is binds in the active site of thrombin with Ki of 0.66 nM, 2xaPTT=0.43 uM). Thrombin inhibitor 1 (Compound 4) is evaluated for its thrombin inhibitory potency and its functional ability to double the activated partial thromboplastin time (2xaPTT) in human plasma with a 2xaPTT of 0.43 μM.|Products are for research use only. Not for human use.|