Product Name :
Salicortin
Description:
Salicortin, a phenolic glycoside, has been isolated from many plants such as Populus and Salix species. Salicortin inhibits osteoclast differentiation and bone resorption by down-regulating JNK and NF-κB/NFATc1 signaling pathways. Salicortin has anti-amnesic, anti-adipogenic, and immune-modulatory activity.
CAS:
1887055-63-1
Molecular Weight:
424.40
Formula:
C20H24O10
Chemical Name:
(2-{[(2S, 3R, 4S, 5S, 6R)-3, 4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methyl (1S)-1-hydroxy-6-oxocyclohex-2-ene-1-carboxylate
Smiles :
OC[C@H]1O[C@@H](OC2=CC=CC=C2COC(=O)[C@]2(O)C=CCCC2=O)[C@H](O)[C@@H](O)[C@@H]1O
InChiKey:
CZDNLUMNELLDDD-JAIJEDJZSA-N
InChi :
InChI=1S/C20H24O10/c21-9-13-15(23)16(24)17(25)18(30-13)29-12-6-2-1-5-11(12)10-28-19(26)20(27)8-4-3-7-14(20)22/h1-2,4-6,8,13,15-18,21,23-25,27H,3,7,9-10H2/t13-,15-,16+,17-,18-,20+/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Salicortin, a phenolic glycoside, has been isolated from many plants such as Populus and Salix species. Salicortin inhibits osteoclast differentiation and bone resorption by down-regulating JNK and NF-κB/NFATc1 signaling pathways. Salicortin has anti-amnesic, anti-adipogenic, and immune-modulatory activity.|Product information|CAS Number: 1887055-63-1|Molecular Weight: 424.40|Formula: C20H24O10|Chemical Name: (2-{[(2S, 3R, 4S, 5S, 6R)-3, 4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methyl (1S)-1-hydroxy-6-oxocyclohex-2-ene-1-carboxylate|Smiles: OC[C@H]1O[C@@H](OC2=CC=CC=C2COC(=O)[C@]2(O)C=CCCC2=O)[C@H](O)[C@@H](O)[C@@H]1O|InChiKey: CZDNLUMNELLDDD-JAIJEDJZSA-N|InChi: InChI=1S/C20H24O10/c21-9-13-15(23)16(24)17(25)18(30-13)29-12-6-2-1-5-11(12)10-28-19(26)20(27)8-4-3-7-14(20)22/h1-2,4-6,8,13,15-18,21,23-25,27H,3,7,9-10H2/t13-,15-,16+,17-,18-,20+/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Dronedarone} MedChemExpress|{Dronedarone} Neuronal Signaling|{Dronedarone} Biological Activity|{Dronedarone} In Vitro|{Dronedarone} manufacturer|{Dronedarone} Autophagy} |Shelf Life: ≥12 months if stored properly.{{XE991} web|{XE991} Potassium Channel|{XE991} Epigenetics|{XE991} Biological Activity|{XE991} References|{XE991} manufacturer} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32461153 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Salicortin (100 μM; 2 hours) almost completely retards the phosphorylation of IκBα.|References:|Nie S, et al. Salicortin inhibits osteoclast differentiation and bone resorption by down-regulating JNK and NF-κB/NFATc1 signaling pathways. Biochem Biophys Res Commun. 2016 Jan 29;470(1):61-67.Products are for research use only. Not for human use.|