HSP70B’ ELISA kit

Description:
Only commercially available ELISA kit for ultra-sensitive HSP70B’ detection in cell lysates, serum, and tissue. Innovative – only source for HSP70B’ ELISA, due to patent protectionFast – results from up to 40 samples in duplicate in less than 4.5 hoursQuantitative – obtain statistically signifcant resultsSave – time and precious sample compared to Western blot analysis The HSP70B’ EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.{{347174-05-4} medchemexpress|{347174-05-4} Biological Activity|{347174-05-4} Formula|{347174-05-4} supplier}