Product Name :
TG 100801 Hydrochloride
Description:
TG100801 or TG-100801 is a dual inhibitor of both VEGFr2 and the Src family (Src and YES) kinases as a topically administered therapeutic candidate in clinical trials for the treatment of age-related macular degeneration. TG100801 is a multi-kinases inhibitor. It is a pro-drug version of TG100572. Age-related macular degeneration (AMD) is the leading cause of blindness in the Western world for those patients aged 50 years or older.
CAS:
1018069-81-2
Molecular Weight:
616.54
Formula:
C33H31Cl2N5O3
Chemical Name:
4-chloro-3-[5-methyl-3-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)-1,2,4-benzotriazin-7-yl]phenyl benzoate hydrochloride
Smiles :
Cl.CC1=CC(=CC2=NN=C(NC3C=CC(=CC=3)OCCN3CCCC3)N=C21)C1=CC(=CC=C1Cl)OC(=O)C1C=CC=CC=1
InChiKey:
VLWKPMDUDFMWBO-UHFFFAOYSA-N
InChi :
InChI=1S/C33H30ClN5O3.ClH/c1-22-19-24(28-21-27(13-14-29(28)34)42-32(40)23-7-3-2-4-8-23)20-30-31(22)36-33(38-37-30)35-25-9-11-26(12-10-25)41-18-17-39-15-5-6-16-39;/h2-4,7-14,19-21H,5-6,15-18H2,1H3,(H,35,36,38);1H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Netarsudil dimesylate} MedChemExpress|{Netarsudil dimesylate} ROCK|{Netarsudil dimesylate} Protocol|{Netarsudil dimesylate} In stock|{Netarsudil dimesylate} manufacturer|{Netarsudil dimesylate} Autophagy}
Shelf Life:
≥360 days if stored properly.{{Lixisenatide} MedChemExpress|{Lixisenatide} GPCR/G Protein|{Lixisenatide} Purity & Documentation|{Lixisenatide} Data Sheet|{Lixisenatide} custom synthesis|{Lixisenatide} Epigenetic Reader Domain}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23399686
Additional information:
TG100801 or TG-100801 is a dual inhibitor of both VEGFr2 and the Src family (Src and YES) kinases as a topically administered therapeutic candidate in clinical trials for the treatment of age-related macular degeneration. TG100801 is a multi-kinases inhibitor. It is a pro-drug version of TG100572. Age-related macular degeneration (AMD) is the leading cause of blindness in the Western world for those patients aged 50 years or older.|Product information|CAS Number: 1018069-81-2|Molecular Weight: 616.54|Formula: C33H31Cl2N5O3|Chemical Name: 4-chloro-3-[5-methyl-3-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)-1,2,4-benzotriazin-7-yl]phenyl benzoate hydrochloride|Smiles: Cl.CC1=CC(=CC2=NN=C(NC3C=CC(=CC=3)OCCN3CCCC3)N=C21)C1=CC(=CC=C1Cl)OC(=O)C1C=CC=CC=1|InChiKey: VLWKPMDUDFMWBO-UHFFFAOYSA-N|InChi: InChI=1S/C33H30ClN5O3.ClH/c1-22-19-24(28-21-27(13-14-29(28)34)42-32(40)23-7-3-2-4-8-23)20-30-31(22)36-33(38-37-30)35-25-9-11-26(12-10-25)41-18-17-39-15-5-6-16-39;/h2-4,7-14,19-21H,5-6,15-18H2,1H3,(H,35,36,38);1H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|