Versity in gut microbiota in comparison to the model group.BT 1 BT two O T1 O T2 D T1 D TFoods 2021, 10,12 ofTable 2. The effects of teas on gut microbial neighborhood richness and diversity. Groups CTRL EtOH BT1 BT2 OT1 OT2 DT1 DT2 Chao 1 11.33 1.70 27.83 two.62 18.97 3.64 19.23 5.26 16.83 two.49 # 17.83 1.55 # 17.03 two.90 # 12.17 two.72 ### Simpson 0.23 0.02 0.12 0.00 0.14 0.02 0.13 0.01 0.21 0.02 ## 0.22 0.03 ## 0.23 0.04 ### 0.32 0.02 ### Shannon 0.78 0.04 1.02 0.01 1.02 0.03 0.97 0.04 0.95 0.02 0.87 0.05 ## 0.91 0.04 # 0.86 0.04 ##Note: CTRL, the manage group; EtOH, the model group; BT1, Dianhong Tea; BT2, Yingde Black Tea; OT1, SIRT2 Inhibitor Molecular Weight Tieguanyin Tea; OT2, Fenghuang Danzong Tea; DT1, Fu Brick Tea; DT2, Selenium-Enriched Dark Tea. Chao 1 reflects neighborhood richness of intestinal flora; Simpson and Shannon reflect community diversity of intestinal flora. p 0.001, the model group compared together with the manage group; # p 0.05, ## p 0.01, ### p 0.001, the tea extract supplementary groups compared together with the model group.Subsequently, to investigate the similarities from the structure and composition with the gut microbial community among distinct fecal samples or groups, beta-diversity evaluation and species abundance cluster analysis have been carried out, respectively. Noticed from Figure 7A, beta-diversity evaluation determined by PCoA evaluation indicated that the microbial structure was remarkably disturbed by chronic alcohol exposure when compared with the control group, however the influence may be inhibited and remedied to typical status by way of the therapy of Tieguanyin Tea (OT1), Fenghuang Danzong Tea (OT2), Fu Brick Tea (DT1), and Plasmodium Inhibitor Purity & Documentation SeleniumEnriched Dark Tea (DT2) extracts. Nevertheless, the microbial structures inside the fecal 25 samples of Foods 2021, ten, x FOR PEER Assessment 13 of Dianhong Tea (BT1) and Yingde Black Tea (BT2) groups had been in accordance with the model group, and the 3 groups had been clearly separated from other groups along PCoA1 (38.6 ). It was also indicated that Dianhong Tea (BT1) and Yingde Black structure brought on by did not Tea (BT2) extracts didn’t considerably inhibit the alter of microbial Tea (BT2) extracts substantially inhibit the transform of microbial structure brought on by chronic alcohol intake. chronic alcohol intake.Figure 7.Figure 7. The effects ofon the structure ofof microbiota in mice affected by chronic alcohol exposure. (A) PCoA evaluation. analysis. The effects of teas teas around the structure microbiota in mice affected by chronic alcohol exposure. (A) PCoA (B) species abundance cluster evaluation at the phylum level. (C) species abundance cluster evaluation in the genus level. CTRL, (B) species abundance cluster evaluation at the phylum level. Tea; species abundance clusterTieguanyin in the genus level. the manage group; EtOH, the model group; BT1, Dianhong (C) BT2, Yingde Black Tea; OT1, analysis Tea; OT2, Fenghuang Danzong Tea; DT1, model group; BT1, Dianhong Tea; BT2, Yingde Black Tea; OT1, Tieguanyin Tea; OT2, CTRL, the handle group; EtOH, theFu Brick Tea; DT2, Selenium-Enriched Dark Tea. Fenghuang Danzong Tea; DT1, Fu Brick Tea; DT2, Selenium-Enriched Dark Tea.As anticipated, the outcomes of species abundance cluster evaluation according to both phylum and genus levels showed that overt transform inside the composition of gut microbiota was observed in the model group compared together with the control group as displayed in Figure 7B,C. Moreover, Tieguanyin Tea (OT1), Fenghuang Danzong Tea (OT2), Fu Brick Tea (DT1), Selenium-Enriched Dark Tea (DT2), and control groups had sim.