Smoothelin Antibody (885424) [Alexa Fluor® 488] Summary
E. coli-derived recombinant human Smoothelin B
Met1-Leu132
Accession # P53814
Met1-Leu132
Accession # P53814
Detects human Smoothelin B in direct ELISAs.
IgG1
Monoclonal
Mouse
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Applications/Dilutions
- Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells
Packaging, Storage & Formulations
Store the unopened product at 2 – 8 °C. Do not use past expiration date.
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Smoothelin Antibody (885424) [Alexa Fluor® 488]
- FLJ35365
- FLJ38597
- Smoothelin
- SMSMO
- SMTN
Background
Smoothelin (SMTN) is a cytoskeletal protein associated with stress fibers. It is 917 amino acids (aa) in length and shares 77% and 82% aa identity with mouse and rat SMTN. SMTN has two major isoforms, A and B with reported molecular weights of approximately 59 and 110 kDa, respectively. Isoform A is associated with visceral smooth muscle cells while isoform B is specific to vascular smooth muscle. Loss of SMTN has been associated with defects in intestinal smooth muscle cell contraction as well as increased arterial pressure and cardiac hypertrophy.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
product targets : Guanylate Cyclase inhibitors