SAR.S83460

P2Y11/P2RY11 Antibody (505214) [Alexa Fluor® 594] Summary

    Immunogen
    NS0 mouse myeloma cell line transfected with human P2Y11/P2RY11
    Accession # Q96G91
    Specificity
    Stains human P2Y11/P2RY11 transfectants but not irrelevant transfectants in flow cytometry.
    Isotype
    IgG1
    Clonality
    Monoclonal
    Host
    Mouse
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Applications/Dilutions

    Dilutions
        Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

    Storage
    Store the unopened product at 2 – 8 °C. Do not use past expiration date.
    Buffer
    Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for P2Y11/P2RY11 Antibody (505214) [Alexa Fluor® 594]

      P2RY11
      P2Y11
      P2Y11P2Y purinoceptor 11
      purinergic receptor P2Y, G-protein coupled, 11
      purinergic receptor P2Y11

Background

P2RY11belongs to the family of G protein-coupled receptors. This family has severalreceptor subtypes with different pharmacological selectivity, which overlaps insome cases, for various adenosine and uridinenucleotides. P2RY11 is coupled to the stimulation of thephosphoinositideand adenylyl cyclase pathways and behaves as a selectivepurinoceptor. Naturally occuring read-through transcripts,resultingfrom intergenic splicing between P2RY11 and an immediately upstream gene (PPAN,encoding peter pan homolog), have been found. Variants in the P2RY11 gene havebeen associated with narcolepsy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : YAP inhibitors

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