GOX.0000000000000654

Lactate Dehydrogenase B Antibody (2057D) [Alexa Fluor® 488] Summary

    Additional Information
    Recombinant Monoclonal Antibody.
    Immunogen
    E. coli-derived recombinant human LDHB
    Met1-Val93
    Accession # P07195
    Specificity
    Detects human LDHB in direct ELISAs and Western blots.
    Isotype
    IgG
    Clonality
    Monoclonal
    Host
    Rabbit
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Applications/Dilutions

    Dilutions
        Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

    Storage
    Store the unopened product at 2 – 8 °C. Do not use past expiration date.
    Buffer
    Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Lactate Dehydrogenase B Antibody (2057D) [Alexa Fluor® 488]

      EC 1.1.1
      EC 1.1.1.27
      Epididymis Secretory Protein Li 281
      HEL-S-281
      Lactate Dehydrogenase B
      LDH heart subunit
      LDHB
      LDH-B
      LDHBD
      LDH-H
      L-lactate dehydrogenase B chain
      Renal Carcinoma Antigen NY-REN-46
      TRG-5

Background

LDHB is one of two subunits of Lactose Dehydrogenasewhich is formed from tetramer arrangements of the A and B subunits.  LDHB is part of the pyruvate fermentation tolactate pathway in which it catalyzes the conversion of L-lactate and NAD topyruvate and NADH.  LDHA is widelyexpressed, with high expression in muscle and brain.  High expression in tumor cells correlateswith low survival rates in various cancers including osteosarcoma, oralsquamous cell carcinoma breast and lung cancers. Unlike Lactose Dehyrogenase A,LDHB mutations are not linked to any disease

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : CFTR inhibitors

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