idr.2016.6418

KCC4/SLC12A7 Antibody (891526) [Alexa Fluor® 594] Summary

    Immunogen
    NS0 mouse myeloma cell line transfected with  human SLC12A7
    Met1-Ser1083
    Accession # Q9Y666
    Specificity
    Detects human SLC12A7 in direct ELISAs.
    Source
    N/A
    Isotype
    IgG1
    Clonality
    Monoclonal
    Host
    Mouse
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Applications/Dilutions

    Dilutions
        Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

    Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
    Buffer
    Supplied at 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for KCC4/SLC12A7 Antibody (891526) [Alexa Fluor® 594]

      DKFZp434F076
      KCC4
      KCC4Electroneutral potassium-chloride cotransporter 4
      K-Cl cotransporter 4
      potassium/chloride transporter KCC4
      SLC12A7
      solute carrier family 12 (potassium/chloride transporters), member 7
      solute carrier family 12 member 7

Background

Cation chloride cotransporters, including the potassium-chloride cotransporters (KCCs), are involved in the electroneutral movement of ions across the plasma membrane. SLC12A7 contains 12 membrane-spanning segments, 8 phosphorylation sites, 7 of which are in the C terminus, and 4 potential N-glycosylation sites. It is important for potassium recycling by siphoning potassium ions after their exit from outer hair cells into supporting Deiters cells, where potassium enters the gap junction pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

product targets : Protease-Activated Receptor (PAR) inhibitors

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