Repeat injections of rhGALNS-A488 in mice resulted in enzyme delivery in the course of growth plate and articular cartilage (Determine 6A, D)
Major chondrocytes as a model of MPS IVA in vitro. A: Alcian blue staining of proteoglycans in 6-7 days cultures. B. Collagen 2 (COL2) and Aggrecan (ACAN) qRT-PCR of RNA…