USP7-IN-5

Product Name : USP7-IN-5Description:USP7-IN-5 is a potent ubiquitin specific protease 7 (USP7) inhibitor extracted from patent WO2017212012A1, example 40, has an IC50 of 49.9 nM.CAS: 2166599-74-0Molecular Weight:641.76Formula: C36H43N5O6Chemical Name: tert-butyl…

Wedelolactone

Product Name : WedelolactoneSequence: Purity: ≥96% (HPLC)Molecular Weight:314.2Solubility : Soluble in DMSO (25mg/ml).Appearance: Yellow-green solidUse/Stability : As indicated on product label or CoA when stored as recommended.Description: IKK inhibitor Wedelolactone…

GNE-9605

Product Name : GNE-9605Description:GNE-9605 is a highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors. Leucine-rich repeat kinase 2 (LRRK2) has drawn significant interest in…

SU11652

Product Name : SU11652Sequence: Purity: ≥98% (HPLC)Molecular Weight:414.9Solubility : Soluble in DMSO (>25 mg/ml).Appearance: Orange solid.Use/Stability : As indicated on product label or CoA when stored as recommended.3011029-58-3 References Stable…

Rp-8-Br-cGMPS

Product Name : Rp-8-Br-cGMPSSequence: Purity: ≥98% (HPLC)Molecular Weight:462.2Solubility : Soluble in water (25mg/ml).Appearance: White lyophilized powder.1936529-65-5 medchemexpress Use/Stability : As indicated on product label or CoA when stored as recommended.…

Eriocalyxin B

Product Name : Eriocalyxin BDescription:Eriocalyxin B is an ent-Kaurene diterpenoid isolated from Chinese herb Isodon eriocalyx. Eriocalyxin B has anti-cancer and anti-infammatory activities. Eriocalyxin B induces cell apoptosis.CAS: 84745-95-9Molecular Weight:344.40Formula:…

NOR-5

Product Name : NOR-5Sequence: Purity: ≥98% (HPLC)Molecular Weight:334.4Solubility : Soluble in DMSO (10mg/ml).Appearance: White to off-white powder.Use/Stability : As indicated on product label or CoA when stored as recommended.Description: Nitric…

Citalopram-d6 oxalate

Product Name : Citalopram-d6 oxalateDescription:Product informationCAS: 1246819-94-2Molecular Weight:420.46Formula: C22H23FN2O5Chemical Name: 1-{3-propyl}-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; oxalic acidSmiles : C()()N(CCCC1(OCC2=CC(=CC=C12)C#N)C1C=CC(F)=CC=1)C()().OC(=O)C(O)=OInChiKey: KTGRHKOEFSJQNS-TXHXQZCNSA-NInChi : InChI=1S/C20H21FN2O.C2H2O4/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;3-1(4)2(5)6/h4-9,12H,3,10-11,14H2,1-2H3;(H,3,4)(H,5,6)/i1D3,2D3;Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient…

Herbacetin

Product Name : HerbacetinDescription:Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects. Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds…

BAM-22P

Product Name : BAM-22PDescription:BAM-22P, a highly potent opioid peptide, is a potent opioid agonist.CAS: 76622-26-9Molecular Weight:2839.22Formula: C130H184N38O31S2Chemical Name: (4S)-4-{-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl]carbamoyl}pentyl]carbamoyl}-3-carbamoylpropyl]carbamoyl}-2-(4-hydroxyphenyl)ethyl]carbamoyl}-2-carboxyethyl]carbamoyl}-3-(methylsulfanyl)propyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-2-(1H-indol-3-yl)ethyl]carbamoyl}-4-{acetamido}acetamido)-3-phenylpropanamido]-4-(methylsulfanyl)butanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-3-methylbutanamido]acetamido}-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}butanoic acidSmiles : CC(C)(NC(=O)(CCCNC(N)=N)NC(=O)(CCCNC(N)=N)NC(=O)(CCSC)NC(=O)(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)(N)CC1=CC=C(O)C=C1)C(=O)NCC(=O)N(CCCNC(N)=N)C(=O)N1CCC1C(=O)N(CCC(O)=O)C(=O)N(CC1=CNC2=CC=CC=C12)C(=O)N(CC1=CNC2=CC=CC=C12)C(=O)N(CCSC)C(=O)N(CC(O)=O)C(=O)N(CC1=CC=C(O)C=C1)C(=O)N(CCC(N)=O)C(=O)N(CCCCN)C(=O)N(CCCNC(N)=N)C(=O)N(CC1=CC=C(O)C=C1)C(=O)NCC(O)=OInChiKey: QYDAFJUKVGVEKO-PKOVDKIBSA-NInChi : InChI=1S/C130H184N38O31S2/c1-70(2)108(167-118(191)88(28-16-52-144-129(138)139)157-112(185)86(26-14-50-142-127(134)135)156-116(189)91(47-55-200-3)159-119(192)95(58-71-19-6-5-7-20-71)153-103(174)67-148-102(173)66-149-109(182)82(132)57-72-31-37-77(169)38-32-72)125(198)150-68-104(175)152-93(29-17-53-145-130(140)141)126(199)168-54-18-30-100(168)124(197)161-90(44-46-105(176)177)115(188)164-98(62-76-65-147-84-24-11-9-22-81(76)84)122(195)165-97(61-75-64-146-83-23-10-8-21-80(75)83)121(194)160-92(48-56-201-4)117(190)166-99(63-106(178)179)123(196)163-96(60-74-35-41-79(171)42-36-74)120(193)158-89(43-45-101(133)172)114(187)154-85(25-12-13-49-131)111(184)155-87(27-15-51-143-128(136)137)113(186)162-94(110(183)151-69-107(180)181)59-73-33-39-78(170)40-34-73/h5-11,19-24,31-42,64-65,70,82,85-100,108,146-147,169-171H,12-18,25-30,43-63,66-69,131-132H2,1-4H3,(H2,133,172)(H,148,173)(H,149,182)(H,150,198)(H,151,183)(H,152,175)(H,153,174)(H,154,187)(H,155,184)(H,156,189)(H,157,185)(H,158,193)(H,159,192)(H,160,194)(H,161,197)(H,162,186)(H,163,196)(H,164,188)(H,165,195)(H,166,190)(H,167,191)(H,176,177)(H,178,179)(H,180,181)(H4,134,135,142)(H4,136,137,143)(H4,138,139,144)(H4,140,141,145)/t82-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,108-/m0/s1Purity: ≥98% (or refer to the…

Fabiatrin

Product Name : FabiatrinDescription:Fabiatrin is a natural product isolated from Przewalskia tangutica.CAS: 18309-73-4Molecular Weight:486.42Formula: C21H26O13Chemical Name: 6-methoxy-7-{oxy}methyl)oxan-2-yl]oxy}-2H-chromen-2-oneSmiles : COC1=CC2C=CC(=O)OC=2C=C1O1O(CO2OC(O)(O)2O)(O)(O)1OInChiKey: AHBJPGDMGKOLJC-OJHUANBKSA-NInChi : InChI=1S/C21H26O13/c1-29-11-4-8-2-3-14(23)32-10(8)5-12(11)33-21-19(28)17(26)16(25)13(34-21)7-31-20-18(27)15(24)9(22)6-30-20/h2-5,9,13,15-22,24-28H,6-7H2,1H3/t9-,13-,15+,16-,17+,18-,19-,20+,21-/m1/s1Purity: ≥98% (or refer to the Certificate of Analysis)Shipping…

Elacytarabine

Product Name : ElacytarabineDescription:Elacytarabine (CP 4055) is a lipid-conjugated derivative of the nucleoside analog cytarabine. Elacytarabine (CP 4055) is an antineoplastic drug with cytotoxicity in solid tumors.CAS: 188181-42-2Molecular Weight:507.66Formula: C27H45N3O6Chemical…

N-Dodecanoyl-L-homoserine lactone

Product Name : N-Dodecanoyl-L-homoserine lactoneSynonym: N--dodecanamide , dDHL , C12-HSLCAS : 137173-46-7Molecular formula:C16H29NO3Molecular Weight : 283.{{1903008-80-9} web|{1903008-80-9} Purity & Documentation|{1903008-80-9} Description|{1903008-80-9} supplier} 4Purity: ≥98% (NMR)Specifications: Purity ≥98% (NMR)|Appearance White powder|Identity…

Calicheamicin

Product Name : CalicheamicinDescription:Calicheamicin, an antitumor antibiotic, is a cytotoxic agent that causes double-strand DNA breaks. Calicheamicin is a DNA synthesis inhibitor.CAS: 108212-75-5Molecular Weight:1368.35Formula: C55H74IN3O21S4Chemical Name: methyl N-oxy}-3-iodo-5, 6-dimethoxy-2-methylbenzoylsulfanyl)-4-hydroxy-6-methyloxan-2-yl]oxy}amino)-3-{oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-1-hydroxy-13-{2-ethylidene}-11-oxobicyclotrideca-4, 9-dien-2,…

7-Methylcoumarin

Product Name : 7-MethylcoumarinSynonym: 7-Methyl-2H-chromen-2-one, NSC19511, BRN0122625CAS : 2445-83-2Molecular formula:C10H8O2Molecular Weight : 160.17Purity: ≥98% (HPLC)Specifications: Purity ≥98% (HPLC)|Appearance White to off-white powder|Identity 1H-NMR|PropertiesSolvents Soluble in DMSO (50mg/ml).{{2222112-77-6} web|{2222112-77-6} Purity &…

Imidazol-1-yl-acetic acid

Product Name : Imidazol-1-yl-acetic acidDescription:Imidazol-1-yl-acetic acid is an endogenous metabolite.CAS: 22884-10-2Molecular Weight:126.11Formula: C5H6N2O2Chemical Name: 2-(1H-imidazol-1-yl)acetic acidSmiles : OC(=O)CN1C=NC=C1InChiKey: QAFBDRSXXHEXGB-UHFFFAOYSA-NInChi : InChI=1S/C5H6N2O2/c8-5(9)3-7-2-1-6-4-7/h1-2,4H,3H2,(H,8,9)Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition:…

TAMRA-PEG4-acid

Product Name : TAMRA-PEG4-acidDescription:TAMRA-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 1909223-02-4Molecular Weight:677.74Formula: C36H43N3O10Chemical Name: 5--2-benzoateSmiles : CN(C)C1=CC2OC3=CC(C=CC3=C(C3=CC=C(C=C3C()=O)C(=O)NCCOCCOCCOCCOCCC(O)=O)C=2C=C1)=(C)CInChiKey: AZESQZROUFRXLP-UHFFFAOYSA-NInChi : InChI=1S/C36H43N3O10/c1-38(2)25-6-9-28-31(22-25)49-32-23-26(39(3)4)7-10-29(32)34(28)27-8-5-24(21-30(27)36(43)44)35(42)37-12-14-46-16-18-48-20-19-47-17-15-45-13-11-33(40)41/h5-10,21-23H,11-20H2,1-4H3,(H2-,37,40,41,42,43,44)Purity: ≥98% (or…

BIO-acetoxime

Product Name : BIO-acetoximeDescription:BIO-acetoxime (BIA) is a potent and selective GSK-3 inhibitor, with IC50s of both 10 nM for GSK-3α/β. BIO-acetoxime has anticonvulsant and anti-infection activity.CAS: 667463-85-6Molecular Weight:398.21Formula: C18H12BrN3O3Chemical Name:…

Everolimus D4

Product Name : Everolimus D4Description:Product informationCAS: 1338452-54-2Molecular Weight:962.25Formula: C53H83NO14Chemical Name: (1R,9S,12S,15R,18R,19R,21R,23S,30S,32S,35R)-1,18-dihydroxy-12--3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclohexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentoneSmiles : C()(O)C()()O1CC(C1OC)C(C)1CC(=O)(C)C=C(C)(O)(OC)C(=O)(C)C(C)C=CC=CC=C(C)(C2CC(C)(O)(O2)C(=O)C(=O)N2CCCC2C(=O)O1)OCInChiKey: HKVAMNSJSFKALM-QDIGKZACSA-NInChi : InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11-,16-12-,33-17-,37-27-/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1/i24D2,25D2Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as…

HMN-176

Product Name : HMN-176Description:HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1), without significant effect on tubulin polymerization.CAS: 173529-10-7Molecular Weight:382.43Formula: C20H18N2O4SChemical Name: N-{6-cyclohexa-2,4-dien-1-ylidene}-4-methoxybenzene-1-sulfonamideSmiles : COC1C=CC(=CC=1)S(=O)(=O)N=C1C=CC=CC1=CC=C1C=CN(O)C=C1InChiKey: MYEJOKLXXLVMPR-RPBJWCAZSA-NInChi…

(rel)-Myrislignan

Product Name : (rel)-MyrislignanDescription:(rel)-Myrislignan, a relative configuration of Myrislignan. Myrislignan is a lignan isolated from Myristica fragrans Houtt.CAS: 52190-21-3Molecular Weight:374.43Formula: C21H26O6Chemical Name: 4--1-hydroxypropyl]-2-methoxyphenolSmiles : C(OC1C(=CC(CC=C)=CC=1OC)OC)(O)C1=CC=C(O)C(=C1)OCInChiKey: ULZFTGWWPHYLGI-ZUOKHONESA-NInChi : InChI=1S/C21H26O6/c1-6-7-14-10-18(25-4)21(19(11-14)26-5)27-13(2)20(23)15-8-9-16(22)17(12-15)24-3/h6,8-13,20,22-23H,1,7H2,2-5H3/t13-,20-/m1/s1Purity: ≥98% (or…

Methylophiopogonone A

Product Name : Methylophiopogonone ADescription:Methylophiopogonone A, a homoisoflavonoid isolated from the tuberous roots of Ophiopogon japonicas, shows anti-inflammatory activity.CAS: 74805-90-6Molecular Weight:340.33Formula: C19H16O6Chemical Name: 3--5,7-dihydroxy-6,8-dimethyl-4H-chromen-4-oneSmiles : CC1C(O)=C(C)C2OC=C(CC3=CC4OCOC=4C=C3)C(=O)C=2C=1OInChiKey: AUTZLTCWRDPAPV-UHFFFAOYSA-NInChi : InChI=1S/C19H16O6/c1-9-16(20)10(2)19-15(17(9)21)18(22)12(7-23-19)5-11-3-4-13-14(6-11)25-8-24-13/h3-4,6-7,20-21H,5,8H2,1-2H3Purity: ≥98%…

Mca-Ala-Pro-Lys(Dnp)-OH

Product Name : Mca-Ala-Pro-Lys(Dnp)-OHDescription:Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung.CAS: 305336-82-7Molecular Weight:696.66Formula: C32H36N6O12Chemical Name: (2S)-6--2-{propanoyl]pyrrolidin-2-yl]formamido}hexanoic acidSmiles :…

DBCO-PEG4-MMAF

Product Name : DBCO-PEG4-MMAFDescription:DBCO-PEG4-MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the tubulin polymerization inhibitor, MMAF, linked via the cleavable linker DBCO-PEG4.CAS: 2360411-65-8Molecular Weight:1266.56Formula: C69H99N7O15Chemical…

JUN76288

Product Name : JUN76288Description:JUN76288, also known WEE1-IN-3, is a potent WEE1 kinase inhibitors useful in treatment of cancer and other proliferative diseases.CAS: 2272976-28-8Molecular Weight:497.59Formula: C28H31N7O2Chemical Name: 6--7'-yl)amino]-1, 2-dihydro-1--2-(2-propen-1-yl)-3H-pyrazolopyrimidin-3-oneSmiles : CC(C)(O)C1=CC=CC(=N1)N1C2=NC(NC3=CC4CN(C)CC5(CC5)C=4C=C3)=NC=C2C(=O)N1CC=CInChiKey:…

CP 339818 hydrochloride

Product Name : CP 339818 hydrochlorideDescription:Product informationCAS: 478341-55-8Molecular Weight:340.89Formula: C21H25ClN2Chemical Name: N-pentan-1-amine hydrochlorideSmiles : Cl.CCCCC/N=C1/C=CN(CC2C=CC=CC=2)C2=CC=CC=C/12InChiKey: JIRISCAPZWLWCG-KGYDJYTLSA-NInChi : InChI=1S/C21H24N2.{{Obiltoxaximab} MedChemExpress|{Obiltoxaximab} Anti-infection|{Obiltoxaximab} Purity & Documentation|{Obiltoxaximab} References|{Obiltoxaximab} manufacturer|{Obiltoxaximab} Epigenetics} ClH/c1-2-3-9-15-22-20-14-16-23(17-18-10-5-4-6-11-18)21-13-8-7-12-19(20)21;/h4-8,10-14,16H,2-3,9,15,17H2,1H3;1H/b22-20-;Purity: ≥98% (or refer…

DSLET

Product Name : DSLETDescription:Product informationCAS: 75644-90-5Molecular Weight:686.75Formula: C33H46N6O10Chemical Name: (2S,3R)-2--3-hydroxypropanamido]acetamido}-3-phenylpropanamido]-4-methylpentanamido]-3-hydroxybutanoic acidSmiles : CC(C)C(NC(=O)(CC1C=CC=CC=1)NC(=O)CNC(=O)(CO)NC(=O)(N)CC1C=CC(O)=CC=1)C(=O)N((C)O)C(O)=OInChiKey: PKSODCLCMBUCPW-BSFORUJOSA-NInChi : InChI=1S/C33H46N6O10/c1-18(2)13-24(32(47)39-28(19(3)41)33(48)49)37-31(46)25(15-20-7-5-4-6-8-20)36-27(43)16-35-30(45)26(17-40)38-29(44)23(34)14-21-9-11-22(42)12-10-21/h4-12,18-19,23-26,28,40-42H,13-17,34H2,1-3H3,(H,35,45)(H,36,43)(H,37,46)(H,38,44)(H,39,47)(H,48,49)/t19-,23+,24-,25+,26+,28+/m1/s1Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as…

Poly(4-vinylphenol)

Product Name : Poly(4-vinylphenol)Description:Poly(4-vinylphenol) is an endogenous metabolite.CAS: 24979-70-2Molecular Weight:164.22Formula: C10H14NOChemical Name: 4-(butan-2-yl)phenol nitrogenSmiles : .CC(CC)C1C=CC(O)=CC=1InChiKey: PPNWQDGVBLJNLI-UHFFFAOYSA-NInChi : InChI=1S/C10H14O.N/c1-3-8(2)9-4-6-10(11)7-5-9;/h4-8,11H,3H2,1-2H3;Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under…

Docosanoic acid

Product Name : Docosanoic acidDescription:Docosanoic acid is poorly absorbed, and a cholesterol-raising saturated fatty acid in humans.CAS: 112-85-6Molecular Weight:340.58Formula: C22H44O2Chemical Name: docosanoic acidSmiles : CCCCCCCCCCCCCCCCCCCCCC(O)=OInChiKey: UKMSUNONTOPOIO-UHFFFAOYSA-NInChi : InChI=1S/C22H44O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h2-21H2,1H3,(H,23,24)Purity: ≥98% (or…

AVN-944

Product Name : AVN-944Description:AVN-944 (VX-944) is an orally available, synthetic small molecule with potential antineoplastic activity. AVN944 inhibits inosine monosphosphate dehydrogenase (IMPDH), an enzyme involved in the de novo synthesis…

Mc-MMAD

Product Name : Mc-MMADDescription:mcMMAD is a novel mc (maleimidocaproyl) linker plus MMAD (Monomethylauristatin D) to be used for prepare antibodies conjugates via cysteine-capped mechanism.CAS: 1401963-15-2Molecular Weight:964.26Formula: C51H77N7O9SChemical Name: 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-carbamoyl}ethyl]pyrrolidin-1-yl]-5-methyl-1-oxoheptan-4-yl](methyl)carbamoyl}-2-methylpropyl]carbamoyl}-2-methylpropyl]-N-methylhexanamideSmiles :…

Tariquidar dihydrochloride

Product Name : Tariquidar dihydrochlorideDescription:Tariquidar dihydrochloride (XR9576 dihydrochloride) is a potent and specific inhibitor of P-glycoprotein (P-gp) with the high affinity (Kd=5.1 nM).CAS: 1992047-62-7Molecular Weight:719.65Formula: C38H40Cl2N4O6Chemical Name: N-phenyl}carbamoyl)-4,5-dimethoxyphenyl]quinoline-3-carboxamide dihydrochlorideSmiles :…

Gluconate sodium

Product Name : Gluconate sodiumDescription:Gluconate sodium (D-Gluconic acid sodium salt) is a corrosion and scale inhibitor of ordinary steel in simulated cooling water.CAS: 527-07-1Molecular Weight:218.14Formula: C6H11NaO7Chemical Name: sodium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoateSmiles :…

11-Hydroxycanthin-6-one

Product Name : 11-Hydroxycanthin-6-oneDescription:11-Hydroxycanthin-6-one, a canthin-6-one alkaloid, is an antitumor agent which shows potent cytotoxic activity.CAS: 75969-83-4Molecular Weight:236.23Formula: C14H8N2O2Chemical Name: 1,6-diazatetracyclohexadeca-3,5(16),7,9,12,14-hexaene-2,11-dioneSmiles : O=C1C=CC2NC=CC3C=2N1C1=CC=CC(=O)C=31InChiKey: IZNXKZBIIFOWPU-UHFFFAOYSA-NInChi : InChI=1S/C14H8N2O2/c17-11-3-1-2-10-13(11)8-6-7-15-9-4-5-12(18)16(10)14(8)9/h1-7,15HPurity: ≥98% (or refer to…

Schisandrin C

Product Name : Schisandrin CDescription:Schizandrin C is a compound that exerts anti-neuroinflammatory effects by upregulating phase II detoxifying/antioxidant enzymes in microglia.CAS: 61301-33-5Molecular Weight:384.42Formula: C22H24O6Chemical Name: 3,22-dimethoxy-12,13-dimethyl-5,7,18,20-tetraoxapentacyclodocosa-1(22),2,4(8),9,15,17(21)-hexaeneSmiles : CC1CC2=CC3OCOC=3C(OC)=C2C2=C(OC)C3OCOC=3C=C2CC1CInChiKey: HTBWBWWADZJXID-UHFFFAOYSA-NInChi :…

WAY-600

Product Name : WAY-600Description:WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM.CAS: 1062159-35-6Molecular Weight:494.59Formula: C28H30N8OChemical Name: 4-(6-(1H-indol-5-yl)-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolopyrimidin-4-yl)morpholineSmiles : C(C1=CN=CC=C1)N1CCC(CC1)N1N=CC2C1=NC(=NC=2N1CCOCC1)C1C=C2C=CNC2=CC=1InChiKey: FPEIJQLXFHKLJV-UHFFFAOYSA-NInChi : InChI=1S/C28H30N8O/c1-2-20(17-29-8-1)19-34-10-6-23(7-11-34)36-28-24(18-31-36)27(35-12-14-37-15-13-35)32-26(33-28)22-3-4-25-21(16-22)5-9-30-25/h1-5,8-9,16-18,23,30H,6-7,10-15,19H2Purity: ≥98% (or…

Nuezhenide

Product Name : NuezhenideDescription:Specnuezhenide ((8E)-Nuezhenide) is isolated from the fruits of Ligustrum lucidum. Specnuezhenide ((8E)-Nuezhenide) can inhibit IL-1β-induced inflammation in chondrocytes via inhibition of NF-κB and wnt/β-catenin signaling. Specnuezhenide ((8E)-Nuezhenide)…

Difloxacin-d3 hydrochloride

Product Name : Difloxacin-d3 hydrochlorideDescription:Difloxacin-d3 (hydrochloride) is the deuterium labeled Difloxacin (hydrochloride).CAS: 1173021-89-0Molecular Weight:438.87Formula: C21H20ClF2N3O3Chemical Name: Smiles : Cl.C()()N1CCN(CC1)C1=CC2=C(C=C1F)C(=O)C(=CN2C1C=CC(F)=CC=1)C(O)=OInChiKey: JFMGBGLSDVIOHL-NIIDSAIPSA-NInChi : InChI=1S/C21H19F2N3O3.ClH/c1-24-6-8-25(9-7-24)19-11-18-15(10-17(19)23)20(27)16(21(28)29)12-26(18)14-4-2-13(22)3-5-14;/h2-5,10-12H,6-9H2,1H3,(H,28,29);1H/i1D3;Purity: ≥98% (or refer to the Certificate of Analysis)Shipping…

Dihydrostreptomycin sulfate

Product Name : Dihydrostreptomycin sulfateDescription:Dihydrostreptomycin sulfate is an aminoglycoside antibiotic, used to treat bacterial diseases in cattle, pigs and sheep.CAS: 5490-27-7Molecular Weight:1461.42Formula: C42H88N14O36S3Chemical Name: bis(N''--6-{oxy}-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy}-2,4,5-trihydroxycyclohexyl]guanidine); tris(sulfuric acid)Smiles : C1O(O2(N=C(N)N)(O)(N=C(N)N)(O)2O)(O2O(CO)(O)(O)2NC)1(O)CO.C1O(O2(N=C(N)N)(O)(N=C(N)N)(O)2O)(O2O(CO)(O)(O)2NC)1(O)CO.OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=OInChiKey: CZWJCQXZZJHHRH-YCRXJPFRSA-NInChi…

Boc-amido-PEG9-amine

Product Name : Boc-amido-PEG9-amineDescription:Boc-amido-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 890091-43-7Molecular Weight:556.69Formula: C25H52N2O11Chemical Name: tert-butyl N-(29-amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosan-1-yl)carbamateSmiles : CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNInChiKey: RTTGVFBQUXJWJG-UHFFFAOYSA-NInChi : InChI=1S/C25H52N2O11/c1-25(2,3)38-24(28)27-5-7-30-9-11-32-13-15-34-17-19-36-21-23-37-22-20-35-18-16-33-14-12-31-10-8-29-6-4-26/h4-23,26H2,1-3H3,(H,27,28)Purity: ≥98%…

Mal-PEG8-acid

Product Name : Mal-PEG8-acidDescription:Mal-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.CAS: 1818294-46-0Molecular Weight:521.56Formula: C23H39NO12Chemical Name: 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acidSmiles : OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=OInChiKey: KLZPPWOSICDUKQ-UHFFFAOYSA-NInChi : InChI=1S/C23H39NO12/c25-21-1-2-22(26)24(21)4-6-30-8-10-32-12-14-34-16-18-36-20-19-35-17-15-33-13-11-31-9-7-29-5-3-23(27)28/h1-2H,3-20H2,(H,27,28)Purity: ≥98% (or…

Acemetacin-d4

Product Name : Acemetacin-d4Description:Product informationCAS: 1196151-16-2Molecular Weight:419.85Formula: C21H18ClNO6Chemical Name: 2--5-methoxy-2-methyl-1H-indol-3-yl}acetyl)oxy]acetic acidSmiles : C1=C(Cl)C()=C()C(C(=O)N2C3=CC=C(C=C3C(CC(=O)OCC(O)=O)=C2C)OC)=C1InChiKey: FSQKKOOTNAMONP-LNFUJOGGSA-NInChi : InChI=1S/C21H18ClNO6/c1-12-16(10-20(26)29-11-19(24)25)17-9-15(28-2)7-8-18(17)23(12)21(27)13-3-5-14(22)6-4-13/h3-9H,10-11H2,1-2H3,(H,24,25)/i3D,4D,5D,6DPurity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as…

1-Triacontanol

Product Name : 1-TriacontanolDescription:1-Triacontanol is a naturally occurring plant growth regulator. 1-Triacontanol is a saturated long-chain alcohol that has growth-promoting activities on a number of plants.CAS: 593-50-0Molecular Weight:438.81Formula: C30H62OChemical Name:…

GSK2292767

Product Name : GSK2292767Description:GSK2292767 is a potent and selective PI3Kδ inhibitor.CAS: 1254036-66-2Molecular Weight:512.58Formula: C24H28N6O5SChemical Name: N--1,3-oxazol-2-yl}-1H-indazol-6-yl)-2-methoxypyridin-3-yl]methanesulfonamideSmiles : COC1N=CC(=CC=1NS(C)(=O)=O)C1=CC2NN=CC=2C(=C1)C1=NC=C(CN2CC(C)OC(C)C2)O1InChiKey: NLUPPCTVKHDVIQ-UHFFFAOYSA-NInChi : InChI=1S/C24H28N6O5S/c1-14-11-30(12-15(2)34-14)13-18-9-26-23(35-18)19-5-16(6-21-20(19)10-27-28-21)17-7-22(29-36(4,31)32)24(33-3)25-8-17/h5-10,14-15,29H,11-13H2,1-4H3,(H,27,28)Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition:…

Phytolaccagenin

Product Name : PhytolaccageninDescription:Phytolaccagenin, a triterpenoid saponin, is the active component of Radix Phytolaccae. Phytolcaccagenin has antifungal activity, anti-inflammatory activity and lower toxicityCAS: 1802-12-6Molecular Weight:532.71Formula: C31H48O7Chemical Name: (2S,4aR,6aS,6bR,8aR,9R,10R,11S,12aR,12bR,14bS)-8a,12b,14b-trihydrogenio-10,11-dihydroxy-9-(hydroxymethyl)-2-(methoxycarbonyl)-2,6a,6b,9,12a-pentamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acidSmiles :…

BMS-191095

Product Name : BMS-191095Description:BMS-191095 is an activators of mitochondrial ATP-sensitive potassium (mitoKATP) channels. Target: potassium channel in vitro: BMS-191095 induces mitochondrial-depolarization and vasodilation. BMS-191095 elicites a dose-dependent vasodilation in endothelium…

BAY-204

Product Name : BAY-204Description:BAY-204 is an inhibitor of Casein kinase 1 alpha and delta(CSNK1a and 5) useful for the treatment of proliferative disorders.CAS: 2468784-57-6Molecular Weight:533.54Formula: C29H26F3N5O2Chemical Name: Smiles : CN1CCC2NC(=C(NC3C=CC=CC=3)C=2C1=O)C1=CC(NC(=O)(CC(F)F)C2=CC=C(F)C=C2)=NC=C1InChiKey:…

Pirlindole

Product Name : PirlindoleDescription:Pirlindole is a selective and reversible MAO-A inhibitor. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3).CAS: 60762-57-4Molecular Weight:226.32Formula: C15H18N2Chemical Name: Smiles : CC1=CC=C2C(=C1)C1CCCC3NCCN2C=13InChiKey: IWVRVEIKCBFZNF-UHFFFAOYSA-NInChi…

2-[(3-hydroxyadamantan-1-yl)amino]acetic acid

Product Name : 2-acetic acidDescription:Product informationCAS: 1032564-18-3Molecular Weight:225.28Formula: C12H19NO3Chemical Name: 3-Hydroxy-1-adamantyl-D-glycineSmiles : O12C3(C(C1)C(C2)C3)NCC(O)=OInChiKey: FSZTVAMKEHAGGP-RKBOTGTGSA-NInChi : InChI=1S/C12H19NO3/c14-10(15)6-13-11-2-8-1-9(3-11)5-12(16,4-8)7-11/h8-9,13,16H,1-7H2,(H,14,15)/t8-,9+,11+,12+Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as…

AM103

Product Name : AM103Description:AM 103 is a potent and selective FLAP inhibitor, with an IC50 value of 4.2 nM.CAS: 1147872-22-7Molecular Weight:632.77Formula: C36H39N3NaO4SChemical Name: 3-methyl}-5--1H-indol-2-yl]-2,2-dimethylpropanoic acid sodiumSmiles : .CC(C)(C)SC1C2=CC(=CC=C2N(CC2C=CC(=CC=2)C2=CN=C(C=C2)OC)C=1CC(C)(C)C(O)=O)OCC1=CC=CC=N1 |^1:0|InChiKey: VANSVYMYESBUFV-UHFFFAOYSA-NInChi…

Tetrazine-Ph-NHS ester

Product Name : Tetrazine-Ph-NHS esterDescription:Tetrazine-Ph-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 1616668-55-3Molecular Weight:313.27Formula: C14H11N5O4Chemical Name: 2,5-dioxopyrrolidin-1-yl 2-acetateSmiles : O=C(CC1C=CC(=CC=1)C1N=NC=NN=1)ON1C(=O)CCC1=OInChiKey: ORWDYVDDJMYIQA-UHFFFAOYSA-NInChi :…

Tos-PEG2-CH2COOH

Product Name : Tos-PEG2-CH2COOHDescription:Tos-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 1807537-35-4Molecular Weight:318.34Formula: C13H18O7SChemical Name: 2-(2-{2-ethoxy}ethoxy)acetic acidSmiles : CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCC(O)=OInChiKey: QQHWSZBWDYTXGD-UHFFFAOYSA-NInChi : InChI=1S/C13H18O7S/c1-11-2-4-12(5-3-11)21(16,17)20-9-8-18-6-7-19-10-13(14)15/h2-5H,6-10H2,1H3,(H,14,15)Purity: ≥98%…

Azido-PEG8-NHBoc

Product Name : Azido-PEG8-NHBocDescription:Azido-PEG8-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.CAS: 2231845-12-6Molecular Weight:538.63Formula: C23H46N4O10Chemical Name: tert-butyl N-(26-azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-yl)carbamateSmiles : CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCN==InChiKey: BDFYYRYBZUPGSL-UHFFFAOYSA-NInChi : InChI=1S/C23H46N4O10/c1-23(2,3)37-22(28)25-4-6-29-8-10-31-12-14-33-16-18-35-20-21-36-19-17-34-15-13-32-11-9-30-7-5-26-27-24/h4-21H2,1-3H3,(H,25,28)Purity: ≥98% (or…

Tectorigenin 7-O-Xylosyl Glucoside

Product Name : Tectorigenin 7-O-Xylosyl GlucosideDescription:Tectorigenin 7-O-Xylosyl Glucoside is a glycosidic isoflavone isolated from Pueraria thomsonii flower.CAS: 231288-19-0Molecular Weight:594.52Formula: C27H30O15Chemical Name: 5-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-7-{oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-oneSmiles : COC1=C(C=C2OC=C(C(=O)C2=C1O)C1C=CC(O)=CC=1)O1O(CO2OC(O)(O)2O)(O)(O)1OInChiKey: MCYJIRFKDCXYCX-YUPZTAPUSA-NInChi : InChI=1S/C27H30O15/c1-37-25-15(6-14-17(21(25)33)18(30)12(7-38-14)10-2-4-11(28)5-3-10)41-27-24(36)22(34)20(32)16(42-27)9-40-26-23(35)19(31)13(29)8-39-26/h2-7,13,16,19-20,22-24,26-29,31-36H,8-9H2,1H3/t13-,16-,19+,20-,22+,23-,24-,26+,27-/m1/s1Purity: ≥98% (or refer…

Iriflophenone

Product Name : IriflophenoneDescription:Iriflophenone, isolated from Aquilaria sinensis, stimulates MCF-7 and T-47D human breast cancer cells proliferation.CAS: 52591-10-3Molecular Weight:246.22Formula: C13H10O5Chemical Name: 2-(4-hydroxybenzoyl)benzene-1,3,5-triolSmiles : OC1C=C(O)C=C(O)C=1C(=O)C1C=CC(O)=CC=1InChiKey: AOJWDTJDEGSHOA-UHFFFAOYSA-NInChi : InChI=1S/C13H10O5/c14-8-3-1-7(2-4-8)13(18)12-10(16)5-9(15)6-11(12)17/h1-6,14-17HPurity: ≥98% (or refer…

Astressin

Product Name : AstressinDescription:Astressin is a potent corticotropin releasing factor (CRF) antagonist.CAS: 170809-51-5Molecular Weight:3563.16Formula: C161H269N49O42Chemical Name: (4S)-4-{carbamoyl}-2-methylbutyl]carbamoyl}-3-carboxypropyl]carbamoyl}pentyl]carbamoyl}-3-methylbutyl]carbamoyl}pentyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-3--6-methyl-2,5,8,12-tetraoxo-1,4,7,13-tetraazacyclooctadecan-9-yl]carbamoyl}-3-carbamoylpropyl]carbamoyl}ethyl]carbamoyl}-3-methylbutyl]carbamoyl}-3-carbamoylpropyl]carbamoyl}-3-carboxypropyl]carbamoyl}ethyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}ethyl]carbamoyl}pentyl]carbamoyl}-3-carboxypropyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-methylpropyl]carbamoyl}-4--3-(1H-imidazol-4-yl)propanamido]-4-methylpentanamido]-4-methylpentanamido]-5-carbamimidamidopentanamido]butanoic acidSmiles : C(CC)(NC(=O)(NC(=O)(CCC(O)=O)NC(=O)(CCCC)NC(=O)(CC(C)C)NC(=O)(CCCCN)NC(=O)(CCCNC(N)=N)NC(=O)(CC(N)=O)NC(=O)1CCCCNC(=O)CC(NC(=O)(CCC(N)=O)NC(=O)(C)NC(=O)(CC(C)C)NC(=O)(CCC(N)=O)NC(=O)(CCC(O)=O)NC(=O)(C)NC(=O)(CCCNC(N)=N)NC(=O)(C)NC(=O)(CCCC)NC(=O)(CCC(O)=O)NC(=O)(CC(C)C)NC(=O)(NC(=O)(CCC(O)=O)NC(=O)(CCCNC(N)=N)NC(=O)(CC(C)C)NC(=O)(CC(C)C)NC(=O)(CC2=CNC=N2)NC(=O)(N)CC2C=CC=CC=2)C(C)C)C(=O)N(C)C(=O)N(CC2=CNC=N2)C(=O)N1)(C)CC)C(N)=OInChiKey: HPYIIXJJVYSMCV-MGDXKYBTSA-NInChi : InChI=1S/C161H269N49O42/c1-23-27-41-96(189-145(239)107(52-59-123(217)218)199-152(246)114(71-84(13)14)207-157(251)126(85(15)16)208-147(241)108(53-60-124(219)220)197-140(234)102(47-38-66-179-161(172)173)193-151(245)112(69-82(9)10)204-153(247)113(70-83(11)12)205-155(249)116(74-94-77-175-79-181-94)201-134(228)95(163)72-92-39-30-29-31-40-92)135(229)182-88(19)130(224)186-100(45-36-64-177-159(168)169)136(230)183-89(20)131(225)188-106(51-58-122(215)216)144(238)195-104(49-56-119(165)212)146(240)202-110(67-80(5)6)149(243)185-90(21)132(226)187-103(48-55-118(164)211)143(237)196-105-50-57-121(214)176-63-35-33-44-99(192-154(248)115(73-93-76-174-78-180-93)200-133(227)91(22)184-137(105)231)142(236)206-117(75-120(166)213)156(250)194-101(46-37-65-178-160(170)171)139(233)190-98(43-32-34-62-162)141(235)203-111(68-81(7)8)150(244)191-97(42-28-24-2)138(232)198-109(54-61-125(221)222)148(242)210-128(87(18)26-4)158(252)209-127(129(167)223)86(17)25-3/h29-31,39-40,76-91,95-117,126-128H,23-28,32-38,41-75,162-163H2,1-22H3,(H2,164,211)(H2,165,212)(H2,166,213)(H2,167,223)(H,174,180)(H,175,181)(H,176,214)(H,182,229)(H,183,230)(H,184,231)(H,185,243)(H,186,224)(H,187,226)(H,188,225)(H,189,239)(H,190,233)(H,191,244)(H,192,248)(H,193,245)(H,194,250)(H,195,238)(H,196,237)(H,197,234)(H,198,232)(H,199,246)(H,200,227)(H,201,228)(H,202,240)(H,203,235)(H,204,247)(H,205,249)(H,206,236)(H,207,251)(H,208,241)(H,209,252)(H,210,242)(H,215,216)(H,217,218)(H,219,220)(H,221,222)(H4,168,169,177)(H4,170,171,178)(H4,172,173,179)/t86-,87-,88-,89-,90-,91-,95+,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,126-,127-,128-/m0/s1Purity: ≥98% (or refer to the Certificate of…

Cbz-NH-PEG3-CH2COOH

Product Name : Cbz-NH-PEG3-CH2COOHDescription:Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.CAS: 462100-05-6Molecular Weight:341.36Formula: C16H23NO7Chemical Name: 2-{2-amino}ethoxy)ethoxy]ethoxy}acetic acidSmiles : OC(=O)COCCOCCOCCNC(=O)OCC1C=CC=CC=1InChiKey: DMBZCDPECWJRJR-UHFFFAOYSA-NInChi : InChI=1S/C16H23NO7/c18-15(19)13-23-11-10-22-9-8-21-7-6-17-16(20)24-12-14-4-2-1-3-5-14/h1-5H,6-13H2,(H,17,20)(H,18,19)Purity: ≥98%…

(±)-Lisofylline-d6

Product Name : (±)-Lisofylline-d6Description:Product informationCAS: 1185995-26-9Molecular Weight:286.36Formula: C13H20N4O3Chemical Name: 1-(5-hydroxyhexyl)-3,7-di(²H₃)methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dioneSmiles : C()()N1C=NC2=C1C(=O)N(CCCCC(C)O)C(=O)N2C()()InChiKey: NSMXQKNUPPXBRG-XERRXZQWSA-NInChi : InChI=1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3/i2D3,3D3Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous…

WAY 208466 dihydrochloride

Product Name : WAY 208466 dihydrochlorideDescription:Product informationCAS: 1207064-61-6Molecular Weight:420.33Formula: C17H20Cl2FN3O2SChemical Name: {2-pyridin-1-yl]ethyl}dimethylamine dihydrochlorideSmiles : Cl.Cl.CN(C)CCN1C=C(C2C=CC=NC1=2)S(=O)(=O)C1C=C(F)C=CC=1InChiKey: BAOHMLBVCLITHA-UHFFFAOYSA-NInChi : InChI=1S/C17H18FN3O2S.2ClH/c1-20(2)9-10-21-12-16(15-7-4-8-19-17(15)21)24(22,23)14-6-3-5-13(18)11-14;;/h3-8,11-12H,9-10H2,1-2H3;2*1HPurity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient…

NGD 94-1

Product Name : NGD 94-1Description:Product informationCAS: 178928-68-2Molecular Weight:320.39Formula: C18H20N6Chemical Name: 2-{4-piperazin-1-yl}pyrimidineSmiles : C(C1=CN=C(N1)C1C=CC=CC=1)N1CCN(CC1)C1N=CC=CN=1InChiKey: OTVQCHUIPJYASM-UHFFFAOYSA-NInChi : InChI=1S/C18H20N6/c1-2-5-15(6-3-1)17-21-13-16(22-17)14-23-9-11-24(12-10-23)18-19-7-4-8-20-18/h1-8,13H,9-12,14H2,(H,21,22)Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as…

Cystamine dihydrochloride

Product Name : Cystamine dihydrochlorideDescription:Product informationCAS: 56-17-7Molecular Weight:225.20Formula: C4H14Cl2N2S2Chemical Name: 2-ethan-1-amine dihydrochlorideSmiles : Cl.Cl.NCCSSCCNInChiKey: YUFRRMZSSPQMOS-UHFFFAOYSA-NInChi : InChI=1S/C4H12N2S2.2ClH/c5-1-3-7-8-4-2-6;;/h1-6H2;2*1HPurity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature…

4-Fluoro-7-nitrobenzofurazan

Product Name : 4-Fluoro-7-nitrobenzofurazanSynonym: IUPAC Name : 4-fluoro-7-nitro-2,1,3-benzoxadiazoleCAS NO.:29270-56-2Molecular Weight : Molecular formula: C6H2FN3O3Smiles: (=O)C1=CC=C(F)C2=NON=C12Description: 4-Chloro-7-nitrobenzofurazan (NBD-chloride) was used in the following studies, Synthesis of fluorescent phospholipid-derivative, NBD-didecanoylphosphatidylethanolamine, Synthesis of…

Enrofloxacin

Product Name : EnrofloxacinSynonym: IUPAC Name : 1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acidCAS NO.:93106-60-6Molecular Weight : Molecular formula: C19H22FN3O3Smiles: CCN1CCN(CC1)C1=C(F)C=C2C(=O)C(=CN(C3CC3)C2=C1)C(O)=ODescription: Enrofloxacin is a broad spectrum antibiotic bactericidal agent used in veterinary medicine to treat…

(7-Azabenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate, 98%

Product Name : (7-Azabenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate, 98%Synonym: IUPAC Name : hexafluoro-λ⁵-phosphanuide; tris(pyrrolidin-1-yl)({3H-triazolopyridin-3-yloxy})phosphaniumCAS NO.Umeclidinium bromide :156311-83-0Molecular Weight : Molecular formula: C17H27F6N7OP2Smiles: F(F)(F)(F)(F)F.Omaveloxolone C1CCN(C1)(ON1N=NC2=CC=CN=C12)(N1CCCC1)N1CCCC1Description: PMID:23551549 MedChemExpress (MCE) offers a wide range of high-quality…

Aloin

Product Name : AloinSynonym: IUPAC Name : (10R)-1,8-dihydroxy-3-(hydroxymethyl)-10--9,10-dihydroanthracen-9-oneCAS NO.:1415-73-2Molecular Weight : Molecular formula: C21H22O9Smiles: OC1O((O)(O)1O)1C2=CC=CC(O)=C2C(=O)C2=C(O)C=C(CO)C=C12Description: Aloe exudant, used as a stimulant-laxativeSelinexor Netupitant PMID:23626759 MedChemExpress (MCE) offers a wide range of…

N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal™ bottles

Product Name : N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal™ bottlesSynonym: IUPAC Name : trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)ethanimidateCAS NO.:25561-30-2Molecular Weight : Molecular formula: C8H18F3NOSi2Smiles: C(C)(C)OC(=N(C)(C)C)C(F)(F)FDescription: N,O-Bis(trimethylsilyl)trifluoroacetamide is used for…

Hemin (porcine), 97+%

Product Name : Hemin (porcine), 97+%Synonym: IUPAC Name : iron(3+) 4,20-bis(2-carboxyethyl)-9,14-diethenyl-5,10,15,19-tetramethyl-21,22,23,24-tetraazapentacyclotetracosa-1(20),2,4,6(24),7,9,11,13(22),14,16,18-undecaene-21,23-diideCAS NO.:16009-13-5Molecular Weight : Molecular formula: C34H32FeN4O4Smiles: .Sacituzumab govitecan CC1=C2C(C=C3N=C(C=C4C(=CC5=NC(=C2)C(C)=C5C=C)C(C)=C4C=C)C(C)=C3CCC(O)=O)=C1CCC(O)=ODescription: Hemin is used in cellular protection and control mechanism.Tegafur-Uracil It…

1-Docosanol, 98%

Product Name : 1-Docosanol, 98%Synonym: IUPAC Name : docosan-1-olCAS NO.:661-19-8Molecular Weight : Molecular formula: C22H46OSmiles: CCCCCCCCCCCCCCCCCCCCCCODescription: Crizotinib Bathophenanthroline PMID:23907051 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and…

Phenanthrene, 97%

Product Name : Phenanthrene, 97%Synonym: IUPAC Name : phenanthreneCAS NO.Donepezil Hydrochloride :85-01-8Molecular Weight : Molecular formula: C14H10Smiles: C1=CC=C2C(C=CC3=CC=CC=C23)=C1Description: Lanosterol PMID:23563799 MedChemExpress (MCE) offers a wide range of high-quality research chemicals…

Flavone, 99+%

Product Name : Flavone, 99+%Synonym: IUPAC Name : 2-phenyl-4H-chromen-4-oneCAS NO.Omaveloxolone :525-82-6Molecular Weight : Molecular formula: C15H10O2Smiles: O=C1C=C(OC2=CC=CC=C12)C1=CC=CC=C1Description: Colistin sulfate PMID:25269910 MedChemExpress (MCE) offers a wide range of high-quality research chemicals…

2-Phenoxypropylamine, 98%

Product Name : 2-Phenoxypropylamine, 98%Synonym: IUPAC Name : 2-phenoxypropan-1-amine hydrochlorideCAS NO.:6437-49-6Molecular Weight : Molecular formula: C9H14ClNOSmiles: Cl.Fexofenadine hydrochloride CC(CN)OC1=CC=CC=C1Description: 2-Phenoxypropylamine is used as pharmaceutical intermediate.Epoprostenol sodium PMID:30125989

4-Methylcatechol, 96%

Product Name : 4-Methylcatechol, 96%Synonym: IUPAC Name : 4-methylbenzene-1,2-diolCAS NO.Asiatic acid :452-86-8Molecular Weight : Molecular formula: C7H8O2Smiles: CC1=CC=C(O)C(O)=C1Description: 4-Methylcatechol is used to synthesize antimicrobial, antioxidant.Omaveloxolone It also acts as effective…

6-Maleimidohexanoic acid

Product Name : 6-Maleimidohexanoic acidSynonym: IUPAC Name : 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoic acidCAS NO.:55750-53-3Molecular Weight : Molecular formula: C10H13NO4Smiles: OC(=O)CCCCCN1C(=O)C=CC1=ODescription: 6-Maleimidohexanoic acid is used as a probe for introducing maleimides groups into biomolecules…

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-p,p’-disulfonic acid, disodium salt hydrat

Product Name : 3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-p,p'-disulfonic acid, disodium salt hydratSynonym: IUPAC Name : disodium 4-benzene-1-sulfonateCAS NO.:1264198-47-1Molecular Weight : Molecular formula: C20H12N4Na2O6S2Smiles: .Galcuronokinase .GDNF Protein, Human S(=O)(=O)C1=CC=C(C=C1)C1=C(N=C(N=N1)C1=CC=CC=N1)C1=CC=C(C=C1)S()(=O)=ODescription: PMID:23833812

Ursolic acid, 95%

Product Name : Ursolic acid, 95%Synonym: IUPAC Name : (1S,2R,4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acidCAS NO.:77-52-1Molecular Weight : Molecular formula: C30H48O3Smiles: C1CC2(CC3(C)C(=CC45(C)CC(O)C(C)(C)5CC34C)21C)C(O)=ODescription: Trimethobenzamide hydrochloride Clopidogrel PMID:23543429

Owfrequencyoffamilialpituitarytumors, thesmallsizeofaffectedfamilies,andtheverylowprevalenceof mutationswithinthesefamilies,costlygeneticscreeningisnotyet convincinglywarranted.Accuraterelativelylow-costmeasurement ofserumIGF1levelsiscurrentlythemosteffectivescreeningfor affectedpatientswithGH-secretingpituitarytumors. Acromegaly

Owfrequencyoffamilialpituitarytumors, thesmallsizeofaffectedfamilies,andtheverylowprevalenceof mutationswithinthesefamilies,costlygeneticscreeningisnotyet convincinglywarranted.Accuraterelativelylow-costmeasurement ofserumIGF1levelsiscurrentlythemosteffectivescreeningfor affectedpatientswithGH-secretingpituitarytumors. Acromegaly remedy Severaltreatmentoptionsarecurrentlyavailableforacromegaly (Table2). Surgery ResectionofGH-secretingpituitaryadenomasistechnicallychallengingbecauseoftheanatomicinaccessibilityofthepituitary andbonysellarconfinesandtheproximityofvitalbrainandvascularstructures.Functioningtumormicrofociofteninvadedural spaces,arenotreadilyvisibleatsurgery,andcontinuetosecrete GHaftertumorresection.GH-secretingtumorshaveapropensitytoinvadelaterallyintothecavernoussinus,precludingsafe resection.Tumor-associatedinternalcarotidarterytortuosityand microaneurysmsalsorequiresurgicalcautionandalertness.Over 90 ofresectionsareperformedviaanendonasaltranssphenoidal strategy,oftenwithminimallyinvasiveendoscopictechniques. ComputerizedimageguidanceandintraoperativeMRIcoupled with improvement of microinstrumentation and optics have resultedinsafe,helpful,andminimallytraumaticprocedures whenperformedbyskilledandexperiencedneurosurgeons(S23).…

Hyl succinimidyl carbonate 1-O-Benzotriazole-N,N,N’,N’-tetramethyl-uromium-hexafluoro-phosphate Hydrochloric acid Histidine

Hyl succinimidyl carbonate 1-O-Benzotriazole-N,N,N',N'-tetramethyl-uromium-hexafluoro-phosphate Hydrochloric acid Histidine 1-Hydroxybenzotriazole High-performance liquid chromatography Higher resolution mass spectra Leucine Lithium hydroxide Methanol Magnesium sulfate Methyltrityl Mass-to-charge ratio Sodium bicarbonateNIH-PA Author Manuscript NIH-PA Author…

P_IGA_357344 Sc3_SNP_IGA_358948 0.0 2.9 4.three five.7 10.2 13.0 14.0 17.5 19.0 22.0 25.1 28.2 29.7 30.3 31.0 34.0 38.7 40.three 41.9 43.four 49.eight 52.9 57.four 57.8 58.4 59.2 60.six 67.0 70.LG3,4-Dimethylstyrene_EJ/AA1,3,8-p-Menthatriene_EJ

P_IGA_357344 Sc3_SNP_IGA_358948 0.0 two.9 4.three five.7 10.2 13.0 14.0 17.five 19.0 22.0 25.1 28.two 29.7 30.three 31.0 34.0 38.7 40.3 41.9 43.four 49.8 52.9 57.four 57.eight 58.4 59.two 60.six 67.0…

(n=49) 103.3sirtuininhibitor5.5 (n=33) 87.5sirtuininhibitor3.2 (n=63) five.25sirtuininhibitor.94 (n=52) ten.6sirtuininhibitor.9 (n=46) two.25sirtuininhibitor.9 (n

(n=49) 103.3sirtuininhibitor5.5 (n=33) 87.5sirtuininhibitor3.2 (n=63) 5.25sirtuininhibitor.94 (n=52) ten.6sirtuininhibitor.9 (n=46) 2.25sirtuininhibitor.9 (n=46) 191.3sirtuininhibitor5.8 (n=67) 55.9sirtuininhibitor1.two (n=64) 122.1sirtuininhibitor4.four (n=64) 129.1sirtuininhibitor7.4 (n=64) 167.2sirtuininhibitor8.0 (n=34) 0.94sirtuininhibitor.eight (n=34) two.47sirtuininhibitor.7 (n=34) 26.5sirtuininhibitor4.7 (n=34) 39.8sirtuininhibitor8.two (n=34) BSM-treated…

Sduringthemetabolicstudy.Hyperlipidemicsubjectsoftenhave delayedLDLapoB-100catabolism(seesupplementalTable S3).Wehavedocumentedalsothatfeedingresultsinmore directTRLapoB-100catabolismandlessconversionofTRL apoB-100toLDLapoB-

Sduringthemetabolicstudy.Hyperlipidemicsubjectsoftenhave delayedLDLapoB-100catabolism(seesupplementalTable S3).Wehavedocumentedalsothatfeedingresultsinmore directTRLapoB-100catabolismandlessconversionofTRL apoB-100toLDLapoB-100,aswellasdelayedLDLapoB-100 catabolism,comparedwiththefastingstate(29).In spite of thedifferences,ourfindingsareconsistentwiththesepreviousstudiesandsupporttheconceptthatapoBinsdLDLs iscatabolizedmoreslowlythanapoBinlbLDLs. Our data indicate that approximately 80 of lbLDL apoB-100isderivedfromTRLapoB-100,withtheremainderMetabolism and proteomics of LDL subfractionsTABLE three. ApolipoproteincompositionoflbLDLandsdLDLduringplaceboandtreatmentwithrosuvastatin40mg/dayPlacebo(totalproteinspectralintensity,logbase2) Proteins lbLDL sdLDL PbRosuvastatin(totalproteinspectralintensity,logbase2)…

IL-6R -Actin Forward primer ATGGAAGAGAC Transthyretin/TTR Protein Biological Activity CTTCAGCTAC GGAATCTTGGA GCGAGTTGT TGCAAAGCTATA GGTGGAGAGCIL-6R -Actin

IL-6R -Actin Forward primer ATGGAAGAGAC Transthyretin/TTR Protein Biological Activity CTTCAGCTAC GGAATCTTGGA GCGAGTTGT TGCAAAGCTATA GGTGGAGAGCIL-6R -Actin Forward primer ATGGAAGAGAC CTTCAGCTAC GGAATCTTGGA GCGAGTTGT TGCAAAGCTATA GGTGGAGAGC AGTTGCCTTCTT GGGACTGA TCATTCAGAGCC AGCTGCCCAT CAAGCCTTTCC TGACAGAGG CATCTGAACCG…

ESNP locationPCR amplification primer sequence (5' ?3') aGccatcGat aGtcGaaacG taGGcacGaat ttGcttGaa tccaaGcGta tGctcaaGaa GcacaataGc GaGatGGtca

ESNP locationPCR amplification primer sequence (5' ?3') aGccatcGat aGtcGaaacG taGGcacGaat ttGcttGaa tccaaGcGta tGctcaaGaa GcacaataGc GaGatGGtca taatcctGGcG atGaGatcc tttGccaaGc tcctccatac GaacctcGca tGGttGaGat aGGGcacttG GttccaGata GctcatcaGG cttttGGaaG GcacaaGcca cccactattt GctcatcaGG cttttGGaaG GcacaaGcca…